No. We suggest to remove the USB keyboard and mouse from the device after you finish your configuration.
We have found case that some incompatible devices may interrupt player from booting.
While player boots up, player checks all the peripherals to make sure everything works as expected.
During the check, if any external devices connected to USB port, some incompatible devices may result in a check fail.
The symptom can be stuck in "checking storage" , and/or wireless network becomes disabled.
We've found few USB keyboards that may cause this issue to happen.
If same issue ever happened to your installation, you can check if any USB keyboard/mouse being connected to the USB port while booting up.
In conclusion we recommend user not to leave the USB device connected after finish the configuration.